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257–258) characterizes the most effective clinicians as“data seekers, data integrators, and critical evaluators of the application of new knowl-edge to clinical cases,” who recognize that “even if something appears to work, newinformation may assist the therapeutic process to work better.” In our opinion, a moreappropriate term for EBP would be evidence-informed practice. The major cause of failure is develop-ment of proliferative vitreoretinopathy (PVR), a com-plex inflammatory reaction involving development ofepiretinal membranes, which are essentially scars formedchiefly by cells of pigment epithelial and glial origin.Epiretinal membranes can exert traction and reopen pre-viously closed retinal tears, create new tears, bulge anddistort the macula (macular pucker), obscure the macula,or cause macular edema (Machemer, 1988; Asaria andGregor, 2002)

The major cause of failure is develop-ment of proliferative vitreoretinopathy (PVR), a com-plex inflammatory reaction involving development ofepiretinal membranes, which are essentially scars formedchiefly by cells of pigment epithelial and glial origin.Epiretinal membranes can exert traction and reopen pre-viously closed retinal tears, create new tears, bulge anddistort the macula (macular pucker), obscure the macula,or cause macular edema (Machemer, 1988; Asaria andGregor, 2002). Neglect may manifest as malnutritionand dehydration. (2004a) Risk factors for cra-nial ischemic complications in giant cell arteritis.